The case discussion method, which involves teaching scientific theory in a framework that students can relate to their own world, is an interdisciplinary pedagogical tool. Therefore, case study exercises can be used to integrate biochemistry with other advanced chemistry courses. The case presented here can be used at the end of a second-semester organic chemistry course or in an introductory biochemistry course. The case is a fact-based, fictional story in which an FDA official must decide whether to carry out the agency's threat to shut down several buyers clubs that import thalidomide from overseas and dispense it to their members for the treatment of AIDS. Students are required to read the body of the case, analyze data, and search for information using limited leads. Using well-considered arguments based on their research, they are asked to come to conclusions about how the element of risk involved in thalidomide distribution is assessed. They apply their knowledge of biochemistry to assess how thalidomide acts at the cellular level and they apply their knowledge of organic chemistry in writing mechanisms of thalidomide hydrolysis and in the design of thalidomide analogs. Students are assessed on their ability to work in groups, to critically analyze scientific data, and to develop public policies based on risk-benefit analysis.
More Information
Citation
Bennett, Nicole ; Cornely, Kathleen. J. Chem. Educ.2001 78 759.
The "Chemistry Teacher Connection" (CTC) is especially for high school chemistry teachers. For only $40/year, it offers an online-only subscription to CLIC along with membership in the Division of Chemical Education, normally $65/year. CTC subscribers receive access to all articles and supplements from 1996 through the current issue.
Through special arrangement with the ACS, JCE High School CLIC is now able to provide subscribers with online access to Chemical & Engineering News articles that have been selected specifically for secondary science instructors and their students.
Occasionally, collections of JCE back issues become available for donation to individual teachers, schools, or libraries. JCE matches collections with interested recipients. Recipients pay shipping costs or pick up the collection.
For journals in other fields of chemistry visit ACS Publications.
Citation
Always in the