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  Home > JCE Print > Journal of Chemical Education > Issues > 2003  > September  >
In the Classroom
Simulating Chromatographic Separations in the Classroom
Charles A. Smith and F. Warren Villaescusa
Department of Chemistry, Our Lady of the Lake University, San Antonio, TX 78207
Cover
September 2003
Vol. 80 No. 9
p. 1023
Abstract
A classroom activity has been developed that allows students to perform chromatographic separations in the classroom through active participation. Using this classroom simulation, students develop a set of rules used to investigate the effect of flow rate, column dimension, particle size, and mobile/stationary phase affinity on chromatographic separations. While performing the simulation, the concepts of longitudinal and eddy diffusion are dramatically illustrated. Students are not only active participants throughout the entire separation; they also directly observe an evolving separation. The simulation allows students to set initial parameters, watch, and directly participate in isocratic and gradient separations occurring in real time.
More Information
*  Citation
 Smith, Charles A.; Villaescusa, F. Warren. J. Chem. Educ. 2003 80 1023.
*  Keywords
 Chromatography; General Chemistry; Instrumental Methods; Introductory / High School Chemistry; Separation Science
*  History
 Created:
Last Updated:		 August 4, 2003
February 28, 2005
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