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I was intrigued with the title
Eicosanoids and Related Compounds in Plants and
Animals because of my interest in eicosanoid biochemistry and the fact that most
biochemistry texts cover the mammalian component (briefly) but
include nothing on plants or other eukaryotic systems. How do
eicosanoids function in plants? I wanted to know.
The driving force for this book was the session
specifically devoted to Non-Mammalian Eicosanoids at each of the
8th, 9th, and 10th International Conferences on
Prostaglandins and Related Compounds. This collection probably
represents one of the first attempts to gather a broad cross-section of
the work in this field. The editors do not wish to repeat
material available in key reviews elsewhere. Instead,
they provide a useful bibliography, including books, review articles
and important works for further reading. Each chapter
incorporates an extensive list of references and the book
includes a subject index. The editors, judging by the numbers of recent
publications, are active researchers in this field.
The book is divided into two sections. The first
covers the enzymes and factors involved in the biosynthesis
of eicosanoids. There is an introductory chapter on
pathways, which includes both animal and plant systems. The next
five chapters examine the diversity and evolutionary aspects
of several proteins: cyclooxygenases; lipooxygenases, both
mammalian and plant; and
5-lipooxygenase-activating-protein. This section concludes with a chapter covering the
production of oxygenated fatty acid derivatives that are produced by
or are active in fungi, as broadly defined.
The second section of the book covers the
functional aspects of eicosanoids and related compounds. Two
chapters dealing with lipoxygenases in plants are followed by
three chapters on eicosanoids in invertebrates, amphibians, and
fish. The second section was of the most interest to me
personally because I was able find answers to my initial question.
How do these eicosanoids work in plants? Not surprisingly,
they function as signal molecules in plants as they do in animals.
The biochemistry of signaling molecules in general,
and specifically those that are lipids, is rapidly expanding.
Having investigated certain aspects of fatty acid metabolism, I
found that this book opened my eyes to all sorts of interesting
research projects. In fact, several chapters in the second section
offered suggestions for future work. As a faculty member in a
small undergraduate department, I am interested in
research projects on systems that are easily adapted for
undergraduate students. I am also interested in projects that can be
related to mammalian systems. This book served as an
excellent introduction to the broad field of eicosanoid chemistry.
I found it a valuable resource of information and I
would expect that my students would be able to grasp the
big picture from the book while identifying further
literature resources which would be useful references.
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