Stereochemistry is often a difficult topic for both science and non-science majors to learn. The topics covered in most undergraduate textbooks, although fundamental, seem very abstract to most students. This manuscript describes two simple exercises that can be used to introduce concepts associated with stereochemistry such as "sameness", superimposability, chirality, enantiomers, optical activity, polarimetry, and racemic mixtures. One exercise compares chirality in hands with the achiral nature of two textbooks. The other exercise involves a murder mystery, the solution of which hinges upon understanding the concept of optical activity, specifically in natural products such as toxins from poisonous mushrooms.
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