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  Home > JCE Print > Journal of Chemical Education > Issues > 2004  > June  >
In the Laboratory
Class Projects in Physical Organic Chemistry: The Hydrolysis of Aspirin
Peter S. Marrs
Department of Chemistry, University of Victoria, Victoria, BC, V8W 3P6, Canada
Cover
June 2004
Vol. 81 No. 6
p. 870
Abstract
A laboratory experiment is described that requires each student to determine the rate constant for the hydrolysis of aspirin at three different pH values. Individual results from each student are compiled to provide a class set of rate constant versus pH data. The students prepare a pH–rate profile for the hydrolysis of aspirin and analyze this profile to determine the mechanism and type of catalysis of the hydrolysis at different pH values.
Supplement
Instructions for the students and notes for the instructor are available.
*  Contents JCE2004p0870W.doc (Microsoft Word)
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More Information
*  Citation
 Marrs, Peter S. J. Chem. Educ. 2004 81 870.
*  Keywords
 Acid–Base Chemistry; Catalysis; Collaborative / Cooperative Learning; Kinetics; Laboratory Instruction; Organic Chemistry
*  History
 Created:
Last Updated:		 May 2, 2004
January 21, 2005
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