JCE Online Journal of Chemical EducationDivision of Chemical Education, American Chemical SocietyAmerican Chemical Society
 | Subscriptions  | Software Orders  | Support  | Contributors  | Advertisers  | 

JCE Print
   Current Issue
 Previous Issues
 Supplements
 Search JCE Index

JCE Digital Library
   ChemInfo
 DigiDemos
 Featured Molecules
 LivTexts
 LrnCom
 QBank
 SymMath
 WebWare

JCE Software
   Latest Releases
 Software & Video
 Downloads
 Support

Only@JCE Online
   JCE Online Store
 JCE HS CLIC
 JCE Discussion Forums
   Biographical Snapshots
 ChemEd Resource Shelf
 Featured Molecules
 Hal's Picks
 Project Chemlab
 Reviewed WWW Sites
 "Web-Ed" Articles

About JCE
   Features
 Publications
 Operations
 Outreach
 Contact Us


  Home > JCE Print > Journal of Chemical Education > Issues > 2006  > December  >
In the Classroom
Chemical Aspects of General Anesthesia: Part I. From Ether to Halothane
Robert Brunsvold
Department of Anesthesiology, Meritcare, Fargo, ND 58123

Daryl L. Ostercamp
Department of Chemistry, Concordia College, Moorhead, MN 56562

Cover
December 2006
Vol. 83 No. 12
p. 1821
Abstract
In this article we summarize the first one hundred and ten years of general anesthesia from 1846 to 1956. Although the medical profession was slow to use ether or chloroform induced anesthesia, by the end of the 19th century significant numbers of surgeons were relying upon these volatile liquids to provide unconsciousness, analgesia, muscle relaxation, and amnesia. Events leading up to the adoption of a "balanced" approach, where a sequence of individual compounds is used rather than a single agent, are described. The process began in 1934 with the first use of thiopental as an intravenous induction anesthetic and was advanced with the use of the muscle relaxant curare in surgery in 1942. Synthesis of a new inhalational anesthetic, halothane, in the 1950s provided the third and final element. Original syntheses of compounds are included, as are correlations of activities with structures.
More Information
*
Citation
Brunsvold, Robert; Ostercamp, Daryl L. J. Chem. Educ. 2006 83 1821.
*
Keywords
Acids / Bases; Analogies / Transfer; Bioorganic Chemistry; Chirality / Optical Activity; Continuing Education; Drugs / Pharmaceuticals; General Public; History / Philosophy; Medicinal Chemistry; Organic Chemistry; Public Understanding / Outreach; Second-Year Undergraduate; Synthesis; Textbooks / Reference Books
*
History
Created:
Last Updated:
10/30/2006
10/31/2006
<< Previous Article Table of Contents Next Article >>
  Home > JCE Print > Journal of Chemical Education > Issues > 2006  > December  > Page 1821


Subscriptions
 Subscription Info
 Order Forms

JCE HS CLIC

Our Secondary School editors work hard to distill all the JCE materials to produce a fraction of particular interest to high school teachers. We call it CLIC.
 JCE HS CLIC

Contributions Welcome
JCE welcomes your submission
 Contributors' Corner

Advertisers
In recent years we have worked hard to better match our advertisers with our readers. When shopping for chemistry education materials, visit our advertisers' WWW sites first.
 Recent Advertisers

Be An Ambassador
Take JCE along on your outreach missions. Copies of the Journal, guest access to JCE Online, our publications catalog, and more are available for your participants.
 Outreach with JCE

Comments to
jceonline@chem.wisc.edu		 Copyright © Division of Chemical Education, Inc., American Chemical Society.
All rights reserved.