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In the Laboratory
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Using Physical Models of Biomolecular Structures To Teach Concepts of Biochemical Structure and Structure Depiction in the Introductory Chemistry Laboratory
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Gordon A. Bain, John Yi, and Mithra Beikmohamadi
Department of Chemistry, University of Wisconsin–Madison, Madison, WI 53706
Timothy M. Herman and Michael A. Patrick
Center for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, WI 53202-3109
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September 2006
Vol. 83 No. 9
p. 1322
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| Abstract |
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Basic concepts of biomolecular structure were introduced to students in the laboratory portion of a large-enrollment first-year chemistry class. Custom-made physical models of α-helices and β-sheets, the zinc finger moiety, β-globin, and green fluorescent protein were used. α-Helix and DNA construction kits were also employed. Students investigated primary, secondary, and tertiary structure of proteins.
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| Supplement |
Instructions for the students, notes for the instructor, a guide for the teaching assistants, and the preparatory tutorials are available.
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Download |
Contents |
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JCE2006p1322W.pdf
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JCE2006p1322W.zip
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Folder JCE2006p1322W containing JCE2006p1322W_1.doc and JCE2006p1322W_2.doc (Microsoft Word) and JCE2006p1322W_1.pmd and JCE2006p1322W_2.pmd (PageMaker).
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| More Information |
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Citation |
Bain, Gordon A.; Yi, John; Beikmohamadi, Mithra; Herman, Timothy M.; Patrick, Michael A. J. Chem. Educ. 2006 83 1322.
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Keywords |
Amino Acids; Biochemistry; First-Year Undergraduate / General; Hands-On Learning / Manipulatives; High School / Introductory Chemistry; Laboratory Instruction; Molecular Modeling; Nucleic Acids / DNA / RNA; Proteins / Peptides
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History |
Created:
Last Updated: |
8/7/2006
8/18/2006
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 Caution! | | Experiments, laboratory exercises, lecture demonstrations, and other descriptions of the use of chemicals, apparatus, instruments, computers, and computer interfaces are presented in the Journal of Chemical Education as illustrative of new or improved ideas or concepts in chemistry instruction and are directed at qualified teachers. Although every effort is made to assure and encourage safe practices and safe use of chemicals, the Journal of Chemical Education cannot assume responsibility for uses made of its published materials. Many chemicals are hazardous. Precautions for the safe use of hazardous chemicals and directions for their proper disposal are described in the Material Safety Data Sheets and on the labels. We strongly urge all those planning to use materials from our pages to make choices and to develop procedures for laboratory and classroom safety in accordance with local needs and situations. |
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